Regional Symposium on Innovation in science and technology

فارسی

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Dosimetric impact of inter-fraction changes of OARs during intensity-modulated radiation treatment of prostate cancer patients

Authors :

Mahdieh Dayyani¹ Laleh Rafat-Motavalli² Elie Hoseinian-Azghadi³ Niloofar Rafat-Motavalli⁴ Hashem Miri-Hakimabad⁵

1- مرکز تخصصی رایوتراپی و انکولوژی رضا 2- دانشگاه فردوسی مشهد 3- مرکز تخصصی رایوتراپی و انکولوژی رضا 4- دانشگاه فردوسی مشهد 5- دانشگاه فردوسی مشهد

Keywords :

Prostate cancer،IMRT،interfraction،Siemens Artiste Linac

Abstract :

This study aimed to evaluate the dosimetric effect of interfractional motion of OARs during treatment and to find a correlation between the delivered dose parameters and morphological shape of OARs in CBCT images. In this respect, 20 prostate cancer patients with 292 image-guided treatment sessions were included in this retrospective study. The treatment DVH parameters of organs at risk (OARs) based on daily CBCTs were compared to the criteria and the planning value. A comprehensive dosimetric analysis was performed on the data. Based on the results, a method was established to predict the OAR dose parameters at the planning stage.