سمپوزیوم منطقه ای نوآوری در علم و فناوری

صفحه اصلی / دومین سمپوزیوم منطقه ای نوآوری در علم و فناوری

Design of DNA Origami-Heparin Nanostructures for the Development of Viral Therapies

نویسندگان :

Sadegh Dastorani¹ Mahmoud Shariati² Reza Hasanzadeh Ghasemi³

1- Ferdowsi University of Mashhad, Department of Mechanical Engineering 2- Ferdowsi University of Mashhad, Department of Mechanical Engineering 3- Hakim Sabzevari University,Department of Mechanical and Aerospace Engineering

کلمات کلیدی :

Virus،DNA Origami،heparin،Linker

چکیده :

Given the increasing prevalence of viral diseases and limitations of current treatments, the development of a new generation of highly effective antiviral drugs with fewer side effects is imperative. This research introduces novel nanostructures based on DNA origami, heparin, and a spermidine-containing linker, which show great potential for targeted drug delivery and the treatment of viral diseases. These nanostructures form stable complexes, enabling efficient transport of antiviral drugs to infected cells. Additionally, the unique properties of these nanostructures make them a promising platform for the development of new antiviral drugs. The results of this study present a promising outlook for the development of a new generation of nanotechnology-based antiviral therapies.

لیست مقالات

لیست مقالات بایگانی شده

بهساز کیفیت توان مبتنی بر جبران‌ساز دینامیکی ولتاژ و حذف انتخابی هارمونیک جریان با استفاده از ترانسفورماتورهای شبکه توزیع

تورج ثابت فر - مجید حسین‌پور

Human health risk assessment of atmospheric dust in Dargaz area NE-Iran

Faeze Khodaverdizade - Mohammad Hosein Mahmudy Gharaie - Roozbeh Shad - Hossein Sadeghi

Development of an Interface for Estimating the GDOP Parameter in the Conceptual Design of Satellite Constellations

Mohammad Haji Jafari - Fateme Sourani - Sahar Aminabadi - Zahra Amini

A new insight of skin organoids

Milad Rezaei - Fatemeh Jameie - Roya Lari

SEROLOGICAL AND MOLECULAR DETECTION OF HIGHLY PATHOGENIC AVIAN INFLUENZA OF LAYER HENS CIRCULATING IN DIYALA GOVERNORATE

Zainab Abd Awan Al-Talabani

Integration of High-Definition simultaneous EEG and fNIRS recording system

Mojtaba Pourdara - Mostafa Khavanin Zadeh - Javad Safaie

Tuning surface structure of BiOI photocatalysts using magnetized methanol: Applied magnetic field

Sara Abolhasani - Ali Ahmadpour - Mostafa Gholizadeh

Study of CO and NO Adsorption Energy on Catalytic Converter

Somayyeh Veiskarami - Ali Nakheai Pour - Ali Mohammadi - Hossein Amini Mashhadi

Monte Carlo modelling of Siemens Artiste linac head and the 160 MLC and assessment of dose maps for IMRT and 3D-CRT plans

Hashem Miri-Hakimabad - Elie Hoseinian-Azghadi - Laleh Rafat-Motavalli - Taylan Tuğrul - Niloofar Rafat-Motavalli - Vida Khodabandeh-Baygi - Mahdieh Dayyani

انقلاب شبکه های زیستی: کاربرد کامپیوترهای کوانتومی در مسیرهای متابولیکی، جهش های ژنتیکی، تعاملات زیستی

سنا محمدعلیزاده رامی

بیشتر