Regional Symposium on Innovation in science and technology

فارسی

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Neural Network-Based Inverse Model for Non-Invasive Estimation of Corneal Mechanical Properties

Authors :

Seyed Sadjad Abedi-Shahri¹ Mitra Baradari² Iman Zoljanahi Oskui³

1- دانشگاه اصفهان 2- دانشگاه صنعتی سهند 3- دانشگاه صنعتی سهند

Keywords :

Cornea،Inverse Problem،Machine Learning،Neural Networks،Ogden Material Model

Abstract :

This study presents a novel approach to estimate corneal mechanical properties using non-contact tonometry data and machine learning techniques. A neural network-based inverse model was developed to predict Ogden material parameters from corneal apex displacement data. The model was trained on simulated data generated via finite element analysis. Rather than employing standard evaluation metrics, the mechanical behavior of the material model was integrated into the model as the loss function, which minimizes the difference in stress fields between predicted and reference data. The method demonstrated strong performance in accurately predicting the mechanical response of the cornea. This approach offers a promising non-invasive diagnostic tool, bridging the gap between clinical measurements and complex biomechanical properties.