Regional Symposium on Innovation in science and technology

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Nanobiosensors as a Revolutionizing Technique for Diagnosing Parasitic Infection Diseases

Authors :

Soheil Sadr¹ Shakiba Nazemian² Alireza Sazmand³ Cinzia Santucciu⁴ Abbas Rahdar⁵ Sadanand Pandey⁶ Hassan Borji⁷

1- Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mas 2- Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mas 3- Department of Pathobiology, Faculty of Veterinary Medicine, Bu-Ali Sina University, Hamedan 6517658978, Iran 4- WOAH and NRL for Echinococcosis, Animal Health, Istituto Zooprofilattico Sperimentale della Sardegna, Sassari, Italy 5- Department of Physics, University of Zabol, Zabol, Iran 6- Department of Chemistry, College of Natural Science, Yeungnam University, 280 Daehak‐Ro, Gyeongsan 38541, Korea 7- Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mas

Keywords :

Nanotechnology،Nanobiosensors،Parasites،Helminth،Protozoa

Abstract :

Abstract- Parasitic infections, including malaria, hydatid cysts, leishmaniasis, and schistosomiasis, remain a significant cause of mortality and morbidity worldwide. In addition to their severe public health impacts, parasitic diseases impose a heavy economic burden on health systems. Control and treatment of zoonotic parasitic infections depend mainly on early and accurate diagnosis. Traditional diagnostic techniques, such as microscopic examinations, immunological methods, such as enzyme-linked immunosorbent assay (ELISA), and molecular tests, such as polymerase chain reaction (PCR), are standard tools for parasite identification. However, these methods are time-consuming and expensive and rely on sophisticated equipment; however, their application has many challenges. Nanobiosensors are novel devices that use nanotechnology and biology to provide new approaches for rapid and accurate diagnosing techniques, and they can detect many biomarkers. Hence, the current review aims to introduce nanobiosensors and their types and review their specific applications in diagnosing parasitic diseases. These sensors use the unique properties of nanomaterials to detect parasite biomarkers with high sensitivity and accuracy. Nanobiosensors can directly detect parasites or their metabolic products, enabling early disease detection. In conclusion, nanobiosensors could be essential in controlling and eradicating parasitic diseases.